This book, written by an international team of experts, is intended to support any physician beginning an ultrasound-guided regional anesthesia practice or for an expert looking to quickly refresh their knowledge of a specific procedure. The first six chapters deal with core anatomy, physical principles, and needling skills, providing readers with the information necessary prior performing blocks. The following 38 chapters address ultrasound-guided blocks for surgeries and chronic pain medicine, with newly described procedures included, such as the Pecs block and approaches to the quadratus lumborum block. Each of these chapters follows a consistent structure including indications, anatomic reminders, a procedural description, clinical tips and tricks, literature review and references. Finally, the remaining five chapters contain bullet-points for a safe and easy daily practice.